Lichen Planus

This 80 years old man referred to our outpatient clinic with erosive lesion on his lower lip and reticular lesion in his buccal membrane also

He goes under biopsy, and the clinical impression was: erosive lichen planus, AK and SCC

The histological findings of mucosal biopsy of the lesion, shows mucosal ulceration and lichenoid infiltration more in favor of erosive LP. Although possibility of actinic cheilitis can not ruled out

Malignant Melanoma

A 25 year old man, known case of Hodgkin lymphoma since 2002 (autologous BMT), complain from tumor like purple and non tender lesion in dorsal left leg

Differential diagnosis: lymphoma, angiosarcoma & other vascular tumors and melanoma

Left leg biopsy performed; the section showed skin tissue with marked infiltration of highly atypical cells in dermis. The invade surface epithelium (or arise from surface epithelium?) tomural necrosis was seen focally, some nesting were seen in the tumoral cells especially in the upper dermis

Diagnosis: malignant neoplasm, undifferentiated

1-amelanotic melanoma

2-high grade lymphoma

IHC requested; S100: strongly positive in infiltrated cells, HMB 45: non specific immunoreactivity

LCA, CD20 & CD45R/O were negative in infiltrated cells

Vascular Mass

a 76-years-old man, who was under hemodialysis treatment, complained of a mass after he had a vascular surgery for an AV fistula on his arm

Basal cell carcinoma